ACTIVITES-ACTIVITIES

ACTIVITES/ ACTIVITIES

2019-2020



UNE CULTURE DE RIGUEUR/ RIGOR IN THE CULTURE OF MORINGA








IMMUNE FONCTION
Immune Function If you are having immune challenges, the Moringa oleifera leaf extract may provide some benefits. Free radicals (also called reactive oxygen species or ROS) are created by a number of environmental pollutants that include tobacco smoke, radiation, toxic chemicals, pesticides, and car exhausts. The free radicals are able to product oxidative changes (similar to the rancidity of rust being formed on iron) that damage animal and human proteins, enzymes, and DNA. These oxidative changes lead to immune dysfunction, additional diseases and premature aging.

The Moringa leaf contains antioxidants (including gallic acid, quercetin and ascorbic acid) that are effective in reducing oxidative DNA damage. These antioxidants were effective in inhibiting protein oxidation, OH(.)-induced deoxyribose degradation, and in scavenging free radicals such as superoxide anion and nitric oxide. In addition, the Moringa leaf was found to interfere with bacterial intracellular communication, (called QS) which regulates the degree of pathology of various organisms. Other QS blockers have had toxicity and dosage issues but Moringa was able to safely block the QS of virulent genes in C. violacein.

Conventional antibacterial agents are contributing to multiresistance in the pathogens. However, there is no resistance with the natural, nontoxic extracts of Moringa, that inhibit just the QS pathogenic activity and not the rate of bacterial growth (1).

The Moringa leaf extract also inhibits the growth of microorganisms such as the gram-negative Pseudomonas aeruginosa (implicated in the hot-tub rash) and the gram-positive Staphylococcus aureus (involved in staph infections) (2).
The leaf also has anti-Herpes simplex virus type 1 activity. A dose of 750mg/kg per day was able to delay skin lesions and reduced the mortality of mice that were infected with HSV-1.
The benefits of the Moringa extract were comparable to acyclovir in mice survival (3) . Beta-sitosterol is a sterol (similar to cholesterol or sex hormones), synthesized by the Moringa tree. This sterol reduces inflammation, cancer risk, fever and modulates immune activity. Beta-sitosterol and its glycoside (beta-sitosterol glycoside) appear to target specific T-helper lymphocytes, the Th1 and Th2 cells, and helps to normalize their function.

This results in improved T-lymphocyte and natural killer cell activity. Researchers have also observed that beta-sitosterol reduces overactive antibody responses and DHEA:cortisol ratios have been normalized. These benefits are especially helpful in chronic viral infections, allergies, cancer and autoimmune disorders (4) .

In addition, the Moringa leaves have about 44 compounds, which have anti-fungal activity in laboratory tests against parasites that cause ringworm, athlete’s foot, jock itch and fingernail fungus (Trichophyton rubrum) and fungi that can cause skin and hair diseases in animals and humans (Microsporum canis) (5) .
The Moringa leaf extract is effective in promoting good health and longevity by reducing disease states and fighting chronic immune dysfunction  .
Our product has the highest quality and purity of ingredients for the Moringa oleifera leaf powder and seeds for highest rate of germination.

References: (1) Singh BN, Singh BR, Singh RL, Prakash D, Dhakarey R, Upadhyay G, Singh HB. Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringa oleifera. Food Chem Toxicol 2009; 47(6): 1109-16. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19425184 (2) Anwar F, Latif S, Ashraf M, Gilani AH. Moringa oleifera: a food plant with multiple medicinal uses. Phytother Res. 2007 Jan;21(1):17-25. http://www.ncbi.nlm.nih.gov/pubmed/17089328 (3) Lipipun V, Kurokawa M, Suttisri R, Taweechotipatr P, Pramvothin P, Hattori M, Shiraki K. Efficacy of Thai medicinal plant extracts against herpes simplex virus type 1 infection in vitro and in vivo. Antiviral Res 2003; 60(3):175-80. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/14638393 (4) Bouic PJ, Lamprecht JH. Plant sterols and sterolines: a review of their immune-modulating properties. Altern Med Rev 1999; 4(3): 170-7. http://www.ncbi.nlm.nih.gov/pubmed/10383481 (5) Chuang P-H, Lee C-W, Chou J-Y, Murugan M, Shieh B-J, Chen H-M. Anti-fungal activity of crude extracts and essential oil of Moringa Oleifera Lam. Bioresource Technology 2007; 98: 232-236. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/16406607